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Judith E Karp Selected Research

17-aminogeldanamycin

11/2011Phase I and pharmacological study of cytarabine and tanespimycin in relapsed and refractory acute leukemia.
7/2005Heat shock protein 90 inhibition sensitizes acute myelogenous leukemia cells to cytarabine.

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Judith E Karp Research Topics

Disease

59Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2021 - 07/2002
37Neoplasms (Cancer)
01/2019 - 07/2002
35Leukemia
11/2021 - 07/2002
13Hematologic Neoplasms (Hematological Malignancy)
11/2017 - 08/2002
6Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
11/2021 - 07/2002
5Mucositis
01/2019 - 06/2005
5Myeloid Leukemia (Leukemia, Myelocytic)
01/2019 - 07/2002
5Myelodysplastic Syndromes (Myelodysplastic Syndrome)
01/2017 - 08/2003
5BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
09/2008 - 07/2002
4Lymphoma (Lymphomas)
11/2018 - 01/2012
4Breast Neoplasms (Breast Cancer)
01/2016 - 08/2003
3B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
03/2014 - 12/2003
3Myeloproliferative Disorders (Myeloproliferative Disorder)
09/2008 - 04/2003
2Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic)
02/2017 - 04/2003
2Stomatitis
02/2015 - 03/2005
2Pathologic Complete Response
11/2012 - 05/2008
2Ataxia Telangiectasia (Louis Bar Syndrome)
10/2012 - 07/2005
2Residual Neoplasm
04/2012 - 01/2009
2Acute Promyelocytic Leukemia
01/2011 - 06/2005
2Pain (Aches)
08/2003 - 04/2003
2Headache (Headaches)
08/2003 - 04/2003
2Dyspnea (Shortness of Breath)
08/2003 - 04/2003
2Fatigue
08/2003 - 04/2003
1Hypoalbuminemia
12/2021
1Acute Biphenotypic Leukemia (Leukemia, Mixed Cell)
11/2021
1Acute Disease
11/2021
1Philadelphia Chromosome
11/2021
1Body Weight (Weight, Body)
01/2019
1Fanconi Anemia (Fanconi's Anemia)
02/2017
1Hypersensitivity (Allergy)
01/2016

Drug/Important Bio-Agent (IBA)

21Cytarabine (Cytosar-U)FDA LinkGeneric
01/2018 - 04/2003
13alvocidib (flavopiridol)IBA
01/2018 - 01/2003
10Mitoxantrone (Novantrone)FDA LinkGeneric
01/2018 - 06/2004
10tipifarnib (R115777)IBA
01/2014 - 07/2002
9Biological ProductsIBA
01/2013 - 08/2003
8Pharmaceutical PreparationsIBA
10/2017 - 04/2003
8Farnesyltranstransferase (Farnesyltransferase)IBA
01/2014 - 07/2002
8Proteins (Proteins, Gene)FDA Link
11/2011 - 09/2002
7veliparibIBA
01/2019 - 05/2010
6Phosphotransferases (Kinase)IBA
01/2016 - 07/2004
5Histone Deacetylase InhibitorsIBA
11/2021 - 01/2005
5Topotecan (Hycamtin)FDA LinkGeneric
11/2017 - 06/2004
5Poly(ADP-ribose) Polymerase InhibitorsIBA
02/2017 - 03/2014
4entinostat (MS 275)IBA
11/2021 - 01/2005
4Carboplatin (JM8)FDA LinkGeneric
11/2017 - 09/2005
4MK-8776IBA
10/2017 - 10/2012
4EnzymesIBA
07/2017 - 09/2003
4Etoposide (VP 16)FDA LinkGeneric
01/2012 - 04/2003
4TransferasesIBA
11/2005 - 09/2003
3Biomarkers (Surrogate Marker)IBA
12/2021 - 01/2014
3LigandsIBA
01/2021 - 10/2007
3DNA (Deoxyribonucleic Acid)IBA
02/2015 - 06/2006
3Ribonucleotide Reductases (Ribonucleotide Reductase)IBA
04/2014 - 09/2007
33-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine)IBA
04/2014 - 09/2007
3Checkpoint Kinase 1IBA
10/2012 - 07/2005
3Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric
10/2009 - 04/2003
3Mitogen-Activated Protein KinasesIBA
07/2005 - 09/2003
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2004 - 04/2003
2Clofarabine (Clolar)FDA Link
11/2021 - 09/2007
2midostaurinIBA
01/2020 - 11/2006
2Temozolomide (Temodar)FDA LinkGeneric
01/2019 - 02/2017
2Daunorubicin (Cerubidine)FDA LinkGeneric
01/2018 - 09/2015
2TOR Serine-Threonine KinasesIBA
01/2016 - 01/2012
2Sorafenib (BAY 43-9006)FDA Link
09/2014 - 10/2007
2fludarabineIBA
04/2014 - 01/2008
2Imatinib Mesylate (Gleevec)FDA Link
06/2012 - 09/2008
217-aminogeldanamycinIBA
11/2011 - 07/2005
2Heat-Shock Proteins (Heat-Shock Protein)IBA
11/2011 - 07/2005
2tanespimycin (17AAG)IBA
11/2011 - 07/2005
2MethyltransferasesIBA
01/2011 - 06/2006
2beta CateninIBA
09/2010 - 08/2002
2AnthracyclinesIBA
04/2010 - 09/2009
2Immunomodulating AgentsIBA
09/2008 - 12/2005
2NucleosidesIBA
01/2008 - 07/2005
2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
07/2004 - 08/2003
2Semaxinib (SU5416)IBA
07/2004 - 08/2003
1AlbuminsIBA
12/2021
1Serum AlbuminIBA
12/2021
1Gemtuzumab (Mylotarg)FDA Link
01/2020
1ivosidenibIBA
01/2020
1venetoclaxIBA
01/2020
1glasdegibIBA
01/2020
1CreatinineIBA
01/2019
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
07/2017
1Histones (Histone)IBA
02/2017
1Poly (ADP-Ribose) Polymerase-1IBA
02/2017
1QuinolonesIBA
02/2015
1Type II DNA Topoisomerases (Topoisomerase II)IBA
02/2015
1vosaroxinIBA
02/2015

Therapy/Procedure

27Therapeutics
11/2017 - 07/2002
8Drug Therapy (Chemotherapy)
10/2015 - 06/2004
2Transplantation
11/2018 - 04/2012
2Precision Medicine
01/2016 - 12/2014
2Induction Chemotherapy
04/2015 - 06/2014
2Homologous Transplantation
11/2012 - 09/2011
1Immunotherapy
11/2021
1Hematopoietic Stem Cell Transplantation
01/2021
1FLAM regimen
07/2017
1Combination Drug Therapy (Combination Chemotherapy)
12/2015
1Adjuvant Chemotherapy
02/2015